Multiplexed library prep doesn’t have to be complicated
Simplify your overlapping multiplex PCR workflows with SLIMamp®
Pillar® Stem-Loop Inhibition-Mediated Amplification (SLIMamp) technology is your solution to overlapping amplicons and complicated workflows.
SLIMamp targeted enrichment chemistry enables specific priming of overlapping target segments for single-tube amplification with as little as 2.5ng input DNA in under 8 hours. SLIMamp is central to all Pillar NGS assays, providing reliable targeted amplification of genomic targets.
See SLIMamp enrichment chemistry in action.
Watch the video.
SLIMamp® delivers precise amplification for
improved productivity
Overlapping amplicons are no problem
SLIMamp chemistry uses primers that prohibit the formation of undesirable amplicons by creating inhibitory stem loop structures that prevent non-specific amplification. With this improved sensitivity, you can achieve targeted results with less input DNA.
Single-tube amplification for seamless automation
Unlike traditional amplicon-based library prep, SLIMamp chemistry precisely amplifies only the intended target, so you don’t have to set up separate PCR reactions. This approach minimizes contamination risks and makes library preparation more amenable to automation.
One-day workflow, 2 hours hands on
The SLIMamp workflow is simple and does not contain ligation steps, so you can go from DNA to sequencer in less then 8 hours.
Precise amplification even
when input DNA is limited
SLIMamp was built to go hand-in-hand with Pillar’s ampPD™ primer design platform and PiVAT® bioinformatics toolkit – so the entire NGS workflow is seamlessly integrated, even for custom genomic targets.
SLIMamp®
Enrichment chemistry that enables single-tube amplification
