Featured Publications

First page of PLOS publication entitled Amplification of overlapping DNA amplicons in a single-tube multiplex PCR for targeted next-generation sequencing of BRCA1 and BRCA2

Amplification of overlapping DNA amplicons in a single-tube multiplex PCR for targeted next-generation sequencing of BRCA1 and BRCA2

  • Desiree Schenk, Gang Song, Yue Ke, Zhaohui Wang
  • PLOSone, July 2017; 12(7): e0181062.
  • This paper outlines Pillar Biosciences’ method and further development of the SLIMamp™ technology, and also describes the results of full-gene BRCA1 and BRCA2 panel as applied to cell line DNA and remnant human DNA samples.
Screenshot of the web view of the JCO Global Oncology article entitled Feasibility Study of Molecular Profiling of Gastric Cancer Specimens From Rwanda

Feasibility study of molecular profiling of gastric cancer specimens from Rwanda

  • Mary D. Chamberlin, Belson Rugwizangoga, Francine B. DeAbreu, Eric Rutaganda, Vincent Dusabejambo, Oswald Habyarimana, Steve Bensen, Gregory J. Tsongalis
  • JGO, April 2017; 10.1200/JGO.2017.009605
  • This publication describes meeting proceedings in which researchers from Dartmouth-Hitchcock Medical Center and the University of Rwanda College of Medicine and Health Sciences describe how they used reagents provided by Pillar Biosciences to create and test a research platform for testing FFPE gastric cancer samples collected in Rwanda in the United States.
Screenshot of the first page of the article entitled "Clinical significance of multiple gene detection with a 22-gene panel in formalin-fixed paraffin-embedded specimens of 207 colorectal cancer patients

Clinical significance of multiple gene detection with a 22-gene panel in formalin-fixed paraffin-embedded specimens of 207 colorectal cancer patients 

  • Xian Hua Gao, Guan Yu Yu, Yong Gang Hong, Wei Lian, Hanumant Chouhan, Yi Xu, Lian Jie Liu, Chen Guang Bai, Wei Zhang
  • IJCO, January 2019; 10.1007/s10147-018-1377-1
  • For this publication, researchers used the ONCO/Reveal Lung and Colon Cancer Panel to detect multiple mutations in FFPE specimens from colorectal cancer patients
Screenshot of the Molecular Cancer letter to the editor entitled "Heterogenous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing"

Heterogenous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing

  • Qiaomei Guo, Junlei Wang, Jianfeng Xiao, Lin Wang, Xiaomeng Hu, Wenjun Yu, Gang Song, Jiatao Lou, JianFeng Chen
  • Molecular Cancer, August 2018; 10.1186/s12943-018-0875-0
  • In this study, researchers used Pillar Biosciences technology to examine concordance between mutations detected in FFPE samples and cfDNA samples from the same patients
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