Lung & Colon Cancer Hotspot Panel

The ONCO-REVEAL Lung and Colon Cancer Hotspot Panel is a focused assay targeting key relevant regions for detection and related to regions associated with targeted therapies for these cancers. 1800 hotspots across 22 genes that require only 2.5ng of input. Targets are based on data across consortiums and groups such as CAP, AMP, NCCN, the COSMIC database as well as clinical trials among others.
  • Compatible with genomic DNA, FFPE and ctDNA
  • Single pool workflow for enhanced sensitivity
  • Coverage uniformity 100% within .15x of the mean
  • Detect down to 1% allele frequency
Lung and Colon Targets
AKT1 ALK BRAF CTNNB1 DDR2 EGFR ERBB2 ERBB4 FBXW7 FGFR1 TP53
FGFR2 FGFR3 KRAS MAP2K1 MET NOTCH1 NRAS PIK3CA PTEN SMAD4 STK11