The Pillar Biosciences ONCO/Reveal BRCA1 & BRCA2 Panel is a streamlined and robust enrichment solution for sequencing the entire BRCA1 and BRCA2 genes. Every base in the coding region is 100% covered plus an additional 20 bp of flanking regions. The assay calls all SNVs and small and medium indels. Multiplex whole blood samples for up to 96 samples per run.


  • Automatable single-well processing
  • Less than 8 hours from sample to library
  • Minimal hands-on time
  • Greater than 99.5% assay sensitivity and specificity
BRCA Panel Statistics
Sample type gDNA
Amplicon # 91
On target rate 99.9% ± 0.2%
Coverage uniformity %>0.20 × Mean Coverage: 98.3% ± 1.3%
%>0.10 × Mean Coverage: 100.0% ± 0.0%
Variant frequency 1-2%

IGV Plot of BRCA2

<h5>Concatenated IGV rendering of targeted regions of BRCA2 gene with an example of relative sequencing depths.</h5>