background image showing a female scientist wearing lab coat, gloves, and safety glasses, looking down as she looks at her analysis.

Senior Scientist

Natick, MA | Full-time      

Job purpose:

We are looking for a Senior Scientist with at least five years of experience with NGS assays, preferably in a regulated environment. The ideal candidate will have experience in NGS-based diagnostic method development and a working knowledge of bioinformatic analysis. This individual is responsible for designing, conducting, and leading advanced assay and product development that is critical to Pillar’s corporate strategies. This position will report to the Senior Director of Technical Operations and will supervise the daily activities of research associates.

Duties and Responsibilities

  • Responsible for the development of robust and reliable targeted sequencing assays using optimized chemistry and advanced analytical techniques.
  • Analyzes data from multiple experiments, formulates conclusions and determines future experiments.
  • Uses innovative concepts and procedures to solve a wide range of difficult technical problems in creative ways.
  • Maintain expert knowledge of state-of-the-art principles/theories.
  • Acts as advisor to top management and customers on technical research studies and applications.
  • Identifies new directions for research and contributes to Pillar’s culture of innovation.
  • Delivers and communicates results to multidisciplinary project teams and provides intellectual input.
  • Prepares and delivers scientific presentations for both internal and external use.
  • Key contributor to high-quality, regulatory documents and scientific publications.
  • Appropriately documents experimental procedures and results according to established guidelines.
  • Ensures compliance with safety programs and procedures including blood borne pathogens, chemical hygiene, and biohazardous material.


    • Ph.D. is preferred, or M.S., or B.S. in Biology, Molecular Biology, Genetics, or related fieldData Science, Computer Science, Engineering, Physics, Mathematics

 Experience, Knowledge, Skills and Abilities:


  • 5 years of wet lab experience; M.S. requires 8+ years’ relevant experience; B.S. requires 10+ years’ relevant experience.
  • Hands-on experience with NGS: designing experiments, preparing libraries, running instruments and processing data.


  • Strong molecular biology skills are required: NGS, PCR, DNA/RNA purification & assay optimization.
  • Detailed knowledge of bioinformatic analysis of complex data and standard best practices is required.
  • Exceptional record keeping and presentation skills is required.
  • Industry experience within a regulated work environment and/or method development is strongly preferred.
  • Self-motivated to work in a fast-paced environment.
  • Strategic thinker, able to understand and interpret data and its practical application, able to analyze problems, identify alternative solutions and recommend and implement resolution.

We offer a competitive compensation and benefits package that includes medical and dental insurance, paid vacation, 401(k), and more. For more information visit Pillar Biosciences Inc. is an Equal Opportunity Employer.

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