The ONCOReveal BRCA1 & BRCA2 Panel is a streamlined and robust enrichment solution for sequencing the entire BRCA1 and BRCA2 genes. Every base in the coding region is 100% covered plus an additional 20 bp of flanking regions. The assay calls all SNVs and small and medium insertions and deletions. Multiplex whole blood samples for up to 96 samples per run.


  • Automatable single-well processing
  • Less than 8 hours from sample to library
  • Minimal hands-on time
  • Greater than 99.5% assay sensitivity and specificity

BRCA Panel Statistics
Sample type gDNA
Amplicon # 91
On target rate 99.9% ± 0.2%
Coverage uniformity %>0.20 × Mean Coverage: 98.3% ± 1.3%
%>0.10 × Mean Coverage: 100.0% ± 0.0%
Variant frequency 20%*

*Lower variant frequency possible. Contact us for details on how to reduce variant frequency in your lab.

Concatenated IGV rendering of targeted regions of BRCA2 gene with an example of relative sequencing depths