News & Events

Pillar in the News

December 11, 2017 08:27 ET
Pillar Biosciences Announces Issuance of China and U.S. Patents Covering SLIMamp™ Technology

NATICK MASSACHUSETTS, Dec. 11, 2017 /PRNEWSWIRE/ – Pillar Biosciences, Inc. a manufacturer of precision next-generation sequencing (NGS) panels and software solutions for robust and cost-effective clinical sequencing, announces that key [more]

NATICK MASSACHUSETTS, Dec. 11, 2017 /PRNEWSWIRE/ – Pillar Biosciences, Inc. a manufacturer of precision next-generation sequencing (NGS) panels and software solutions for robust and cost-effective clinical sequencing, announces that key patents covering its SLIMamp™ technology have been issued in its most important markets China and the United States. The State Intellectual Property Office (SIPO) of the People’s Republic of China issued patent ZL201680001111.1 with a duration of 20 years. Building on a prior March 2017 approval by the United States Patent and Trademark Office (USPTO) (U.S. Patent No. 9,605,305, “Method for reducing primer-dimer amplification”), this technology is central to Pillar Biosciences’ vision of enabling affordable precision medicine by simplifying the sample processing workflow while simultaneously improving assay reliability and lowering costs.

“This patent issuance in China is a significant milestone for Pillar Biosciences,” said Gang Song, Ph.D., CEO of Pillar Biosciences. “We are pleased that the SIPO recognizes this fundamental innovation to streamline and accelerate the pace of adoption of precision medicine in mainland China by offering intellectual property protection to this substantial and fast-growing market”, Dr. Song added.

Pillar Biosciences’ SLIMamp technology reduces the time and effort of targeted sequencing enrichment down to a single-day, single-well per sample workflow with minimal sample input (as little as 2.5 nanograms of nucleic acid, or the equivalent of 700 cells). Limited amounts of input material are often challenging for clinical oncology laboratories, and alternative approaches may often take several days to perform.

“With the key US and China patents being issued and a current product portfolio of research use only targeted enrichment kits that include the ONCO/Reveal BRCA1 & BRCA2 Panel, a Lung and Colon Cancer Hotspot Panel, and a multi-cancer Solid Tumor Hotspot Panel, we expect to launch several exciting products in 2018 including one for liquid biopsy” said Manfred Scholz, Ph.D., Head of Corporate Development at Pillar Biosciences. “We are an innovative, technology-driven company that works with clinical, commercial, and technology partners on enabling affordable precision medicine in major global markets.”

About Pillar Biosciences

Pillar Biosciences is a clinical cancer diagnostics company. We create precision next-generation sequencing (NGS) panels and software solutions to make clinical NGS robust, streamlined and cost-effective. Our SLIMamp™- and PiVAT™-based products are intended to deliver the most value to high-throughput reference labs and clinical oncology laboratories. To learn more, visit https://pillar biosciences.com.

Press Contact:

Dale Yuzuki, M.A. M.Ed., Senior Business Development Manager
pr@pillar-biosciences.com

Pillar in the News

November 29, 2017 02:10 ET
Pillar Biosciences announces ISO 13485:2016 Certification

NATICK MASSACHUSETTS, Nov. 29, 2017 /PRNEWSWIRE/ – Pillar Biosciences, Inc. a manufacturer of precision next-generation sequencing (NGS) panels and software solutions for robust and cost-effective clinical sequencing, announces it has [more]

NATICK MASSACHUSETTS, Nov. 29, 2017 /PRNEWSWIRE/ - Pillar Biosciences, Inc. a manufacturer of precision next-generation sequencing (NGS) panels and software solutions for robust and cost-effective clinical sequencing, announces it has received ISO 13485:2016 certification for design, development, manufacture, and distribution of products for the clinical oncology laboratory within a comprehensive quality management system (QMS). The first Pillar Biosciences assay produced under this QMS is the recently-launched ONCO/REVEAL BRCA 1/2 panel targeting the entire coding region of the BRCA genes. All current products are based upon Pillar Biosciences’ patented SLIMamp™ targeted sequencing technology platform and proprietary PiVAT™ analytics software. While current products are for research use only (RUO), Pillar intends to file selected targeted NGS panels with proven clinical utility for regulatory approval.

The ISO 13485:2016 certificate was issued to Pillar Biosciences by Intertek on November 24, 2017. Pillar Biosciences’ Quality Management System will assure the quality and efficacy of its products and services in accordance to applicable regulatory and statutory requirements.

Gang Song, Ph.D., CEO, stated “Pillar Biosciences is enabling affordable precision medicine by producing products for the clinical NGS laboratory that are accurate, streamlined, reliable and cost-effective. Our customers can be confident that Pillar Biosciences’ future RUO and Illumina MiSeq™ Dx in vitro diagnostic products are developed, manufactured, and distributed under the most recent quality standards.”

About Pillar Biosciences

Pillar Biosciences is a clinical cancer diagnostics company. We create precision next-generation sequencing (NGS) panels and software solutions to make clinical NGS robust, streamlined and cost-effective. Our SLIMamp™- and PiVAT™-based products are intended to deliver the most value to high-throughput reference labs and clinical oncology laboratories. To learn more, visit https://pillar‑biosciences.com.

Press Contact:
Dale Yuzuki, M.A. M.Ed., Global Market Development Manager
pr@pillar-biosciences.com

Pillar in the News

October 26, 2017 12:15 ET
Pillar Biosciences to Collaborate with Illumina on Next-Generation Sequencing Based In Vitro Diagnostics Development

Illumina and Pillar Biosciences, Inc. today announced an agreement to develop next-generation sequencing (NGS) based in vitro diagnostic (IVD) tests. Under the terms of the agreement, Pillar Biosciences will lead [more]

Illumina and Pillar Biosciences, Inc. today announced an agreement to develop next-generation sequencing (NGS) based in vitro diagnostic (IVD) tests. Under the terms of the agreement, Pillar Biosciences will lead the development of a series of diagnostic tests that will be run on the Illumina MiSeq™Dx instrument.

Pillar Biosciences has developed Stem Loop Inhibition Mediated Amplification (SLIMamp®), an innovative technology to maximize the efficiency and performance of targeted NGS panels for the clinical user.

Gang Song, Ph.D., CEO of Pillar Biosciences, stated: “The combination of two state-of the-art NGS technologies, SLIMamp and MiSeqDx, will enable affordable precision medicine and make NGS accessible to clinical laboratories.”

The SLIMamp technology is optimized for highly multiplexed reactions from a single tube with as little as 2.5 ng of DNA, supporting sequencing from FFPE and biofluids. Specifically designed to enable automation, it offers a unique technology that can leverage the power of the MiSeqDx to provide superior uniformity and specificity. SLIMamp based NGS panels provide highly sensitive variant detection in regions of interest including GC-rich regions and low quality samples. Pillar intends to submit multiple NGS assays to the FDA starting in 2018.

About Pillar Biosciences

Pillar Biosciences is a clinical cancer diagnostics company. We create precision NGS panels and software solutions to make clinical NGS fast and cost-effective. Our SLIMamp based products are intended to deliver the most value to high-throughput reference labs and clinical oncology labs. To learn more, visit https://pillar-biosciences.com/.

About Illumina

Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as the global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit www.illumina.com and follow @illumina.

Pillar in the News

May 11, 2016 09:00 ET
ORI Healthcare Fund Invests in Pillar Biosciences

HONG KONG, CHINA—(Marketwired - May 11, 2016) - ORI Healthcare Fund L.P. (ORI Fund) announces the completion of US$18 million investment into Pillar Biosciences Inc., a Boston-based start-up specialized in next generation sequencing ("NGS")-based clinical oncology testing in order to bring affordable precision medicine to cancer patients globally. [more]

HONG KONG, CHINA—(Marketwired - May 11, 2016) - ORI Healthcare Fund L.P. (ORI Fund) announces the completion of US$18 million investment into Pillar Biosciences Inc., a Boston-based start-up specialized in next generation sequencing ("NGS")-based clinical oncology testing in order to bring affordable precision medicine to cancer patients globally.

Pillar Biosciences is prized with its patent-pending targeted sequencing technology platform and a proprietary data analysis toolkit, which achieve high sensitivity and specificity with clinical samples. The platform provides a fast, simple and affordable targeted sequencing method for NGS-based oncology testing. The start-up has also released its beta version of Lung & Colon Cancer Somatic Mutation Panel and BRCA1 & BRCA2 Germline Mutation Panel to cancer centers and clinical testing companies in US and China for validation studies.

The investment from ORI Fund will help the company continue its R&D efforts in tumor tissue genotyping area, i.e. integration of back-end information analytics capability, as well as adding liquid biopsy products for cancer therapeutic decision-making and treatment monitoring.

ORI Capital, the manager of ORI Fund, believes that NGS-based oncology testing is an integral component of precision cancer therapeutics and it helps to make steady advances in the molecular diagnosis of cancers. In particular, NGS makes it possible to detect cancer in early stages by directly measuring circulating tumor DNA.

The transaction is consistent with ORI Fund's investment focus in the clinical oncology space. "We are excited to partner with Pillar Biosciences to further advance the modern cancer treatment, which is the main focus of our fund," commented Ms. Simone Song, Senior Partner of ORI Fund. "We hope the partnership between us will help speed up the development of affordable precision treatments for cancer patients worldwide."

About ORI Healthcare Fund

ORI Fund is a US$200 million venture capital fund focused on investing in innovative companies with disruptive technologies in the healthcare industry globally. The fund is founded by Ms. Simone (Hong Fang) Song, former investment banker and head of China Healthcare at Goldman Sachs. The team consists mostly of former Goldman Sachs bankers and healthcare scientists.