ONCOReveal Lung cfDNA Panel

The ONCOReveal Lung cfDNA Panel is a targeted circulating free DNA (cfDNA)-based liquid biopsy solution for the sensitive detection of resistance or driver mutations from plasma samples. There is currently a large interest in using circulating tumor DNA detection in the bloodstream for treatment monitoring, for treatment sensitivity, as well as for its potential use for early detection.

Benefits:

  • Streamlined single-well processing approach
  • High on-target rate
  • Targets 17 known lung cancer oncogenes
Unique Variants
Sample type circulating free DNA (cfDNA)
DNA input 20 ng cfDNA
Amplicon # 81
On target rate 93.2% ± 2.85%
Coverage uniformity %>0.20 × Mean: 99.8% ± 0.7% %>0.15 × Mean: 100.0% ± 0.0%
Variant frequency 0.1%-0.2%
Lung Circulating Tumor DNA Panel Target Genes (17 in total)
AKT1 ERBB4 NRAS
ALK FGFR1 PIK3CA
BRAF FGFR3 PTEN
DDR2 KRAS STK11
EGFR MAP2K1 TP53
ERBB2 MET